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Sekisui XenoTech
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Journal: American Journal of Cancer Research
Article Title: Dysregulation and activities of ubiquitin specific peptidase 2b in the pathogenesis of hepatocellular carcinoma
doi:
Figure Lengend Snippet: USP2 protein expression levels were reduced in HCC-T tissues from HCC patients. (A) Representative total USP2 protein staining with goat anti-human USP2 IgG in the tissues of human normal liver (n=76), HCC-NT (n=38) and HCC-T (n=115) by IHC. As negative controls, human normal liver tissues (n=6) were also stained with goat pre-immune serum. (B) Quantification of the USP2 protein levels were performed with ImageJ. (C) Representative USP2 protein staining in four paired HCC-T and HCC-NT tissues (n=10) by IHC. (D) USP2 protein levels in ten paired HCC-NT and HCC-T tissues as groups as well as (E) individual pairs. **P<0.01 and ***P<0.001 in students’ t-test for pair-wise comparison or one-way ANOVA, followed by Tukey post-hoc test for multiple comparisons.
Article Snippet: Human liver samples Human liver tissue microarray slides including a total of 76 normal, 38 HCC-NT and 115 HCC-T samples with 10 pairs of HCC-NT and
Techniques: Expressing, Staining
Journal: American Journal of Cancer Research
Article Title: Dysregulation and activities of ubiquitin specific peptidase 2b in the pathogenesis of hepatocellular carcinoma
doi:
Figure Lengend Snippet: USP2 mRNA expression levels were decreased in HCC-T tissues from HCC patients. (A) The expression levels of USP2 mRNA in human normal liver (n=12), HCC-NT (n=8) and HCC-T (n=21) detected by real-time PCR. (B) The expression levels of USP2 mRNA in paired HCC-NT and HCC-T tissues as groups as well as (C) individual pairs (n=8). *P<0.05 and **P<0.01 in students’ t-test for pair-wise comparison or one-way ANOVA, followed by Tukey post-hoc test for multiple comparisons.
Article Snippet: Human liver samples Human liver tissue microarray slides including a total of 76 normal, 38 HCC-NT and 115 HCC-T samples with 10 pairs of HCC-NT and
Techniques: Expressing, Real-time Polymerase Chain Reaction
Journal: American Journal of Cancer Research
Article Title: Dysregulation and activities of ubiquitin specific peptidase 2b in the pathogenesis of hepatocellular carcinoma
doi:
Figure Lengend Snippet: Dysregulation of Usp2 mRNA expression in HCC-T tissues from HCC mice. A. The expression levels of Usp2 mRNA in mouse normal liver (n=16), HCC-NT (n=15) and HCC-T (n=15) samples. B. The expression levels of USP2 mRNA in paired HCC-T and HCC-NT tissues. **P<0.01 and ***P<0.001 in students’ t-test for pair-wise comparison or one-way ANOVA, followed by Tukey post-hoc test for multiple comparisons.
Article Snippet: Human liver samples Human liver tissue microarray slides including a total of 76 normal, 38 HCC-NT and 115 HCC-T samples with 10 pairs of HCC-NT and
Techniques: Expressing
Journal: American Journal of Cancer Research
Article Title: Dysregulation and activities of ubiquitin specific peptidase 2b in the pathogenesis of hepatocellular carcinoma
doi:
Figure Lengend Snippet: USP2b mRNA expression levels were markedly reduced in HCC-T tissues from HCC patients. (A) The expression levels of USP2 mRNA in human normal liver (n=12), HCC-NT (n=8) and HCC-T (n=21) detected by real-time PCR. (B) USP2b protein detected by Western blot in normal liver (n=8), HCC-NT (n=8) and HCC-T tissues (n=8). (C) Quantification of the USP2b protein levels in (B) by ImageJ. (D) The expression levels of USP2 mRNA in paired HCC-NT and HCC-T tissues as groups as well as (E) individual pairs (n=8). ***P<0.001 in students’ t-test for pair-wise comparison or one-way ANOVA, followed by Tukey post-hoc test for multiple comparisons.
Article Snippet: Human liver samples Human liver tissue microarray slides including a total of 76 normal, 38 HCC-NT and 115 HCC-T samples with 10 pairs of HCC-NT and
Techniques: Expressing, Real-time Polymerase Chain Reaction, Western Blot
Journal: American Journal of Cancer Research
Article Title: Dysregulation and activities of ubiquitin specific peptidase 2b in the pathogenesis of hepatocellular carcinoma
doi:
Figure Lengend Snippet: Usp2b mRNA expression levels were significantly deceased in HCC-T tissues from HCC mice. (A) The expression levels of Usp2b mRNA in mouse normal liver (n=16), HCC-NT (n=26) and HCC-T (n=26) samples. (B) The expression levels of Usp2b mRNA in paired HCC-T and HCC-NT tissues (n=26). (C) Representative Western blots of Usp2b protein in normal liver (n=18), HCC-NT (n=18) and HCC-T tissues (n=17). (D) Quantification of Usp2b protein in (C) by ImageJ. *P<0.05, **P<0.01 and ***P<0.001 in one-way ANOVA, followed by Tukey post-hoc test for multiple comparisons.
Article Snippet: Human liver samples Human liver tissue microarray slides including a total of 76 normal, 38 HCC-NT and 115 HCC-T samples with 10 pairs of HCC-NT and
Techniques: Expressing, Western Blot